Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma

BACKGROUND: Cancer therapy targeting programmed death receptor-1 (PD-1 or CD279) or programmed death-ligand 1 (PD-L1 or CD274) gives hope to Tongue Squamous Cell Carcinoma (TSCC) treatment. However, the tumor-intrinsic mechanism of PD-L1 is not fully elucidated in TSCC. On the other hand, lycopene s...

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Detalles Bibliográficos
Autores principales: Peng, Mingjing, Fan, Songqing, Li, Junjun, Zhou, Xiao, Liao, Qianjin, Tang, Faqing, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903509/
https://www.ncbi.nlm.nih.gov/pubmed/35164673
http://dx.doi.org/10.1186/s12263-022-00705-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903509/
https://www.ncbi.nlm.nih.gov/pubmed/35164673
http://dx.doi.org/10.1186/s12263-022-00705-y

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