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Exosomal lncRNA TUG1 from cancer-associated fibroblasts promotes liver cancer cell migration, invasion, and glycolysis by regulating the miR-524-5p/SIX1 axis

BACKGROUND: Increasing evidence suggests that taurine upregulated gene 1 (TUG1) is crucial for tumor progression; however, its role in hepatocellular carcinoma (HCC) and the underlying mechanisms are not well characterized. METHODS: The expression levels of TUG1, miR-524-5p, and sine oculis homeobox...

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Detalles Bibliográficos
Autores principales: Lu, Le, Huang, Jingjing, Mo, Jiantao, Da, Xuanbo, Li, Qiaoxin, Fan, Meng, Lu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903597/
https://www.ncbi.nlm.nih.gov/pubmed/35193488
http://dx.doi.org/10.1186/s11658-022-00309-9