LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants

BACKGROUND: Tbr1 encodes a T-box transcription factor and is considered a high confidence autism spectrum disorder (ASD) gene. Tbr1 is expressed in the postmitotic excitatory neurons of the deep neocortical layers 5 and 6. Postnatally and neonatally, Tbr1 conditional mutants (CKOs) have immature den...

Descripción completa

Detalles Bibliográficos
Autores principales: Fazel Darbandi, Siavash, Nelson, Andrew D., Pai, Emily Ling-lin, Bender, Kevin J., Rubenstein, John L. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903688/
https://www.ncbi.nlm.nih.gov/pubmed/35123407
http://dx.doi.org/10.1186/s11689-022-09421-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903688/
https://www.ncbi.nlm.nih.gov/pubmed/35123407
http://dx.doi.org/10.1186/s11689-022-09421-5

Ejemplares similares