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Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT(1) receptors

BACKGROUND: 5-Hydroxytryptamine (5-HT) receptors 1B, 1D and 1F have key roles in migraine pharmacotherapy. Selective agonists targeting these receptors, such as triptans and ditans, are effective in aborting acute migraine attacks and inhibit the in vivo release of calcitonin gene-related peptide (C...

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Detalles Bibliográficos
Autores principales: Edvinsson, Jacob C. A., Maddahi, Aida, Christiansen, Isabella M., Reducha, Philip V., Warfvinge, Karin, Sheykhzade, Majid, Edvinsson, Lars, Haanes, Kristian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903724/
https://www.ncbi.nlm.nih.gov/pubmed/35177004
http://dx.doi.org/10.1186/s10194-022-01394-z