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Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit

Pregnancy 25-hydroxyvitamin D [25(OH)D] concentrations are associated with maternal and fetal health outcomes. Using physiological human placental perfusion and villous explants, we investigate the role of the placenta in regulating the relationships between maternal 25(OH)D and fetal physiology. We...

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Detalles Bibliográficos
Autores principales: Ashley, Brogan, Simner, Claire, Manousopoulou, Antigoni, Jenkinson, Carl, Hey, Felicity, Frost, Jennifer M, Rezwan, Faisal I, White, Cory H, Lofthouse, Emma M, Hyde, Emily, Cooke, Laura DF, Barton, Sheila, Mahon, Pamela, Curtis, Elizabeth M, Moon, Rebecca J, Crozier, Sarah R, Inskip, Hazel M, Godfrey, Keith M, Holloway, John W, Cooper, Cyrus, Jones, Kerry S, Lewis, Rohan M, Hewison, Martin, Garbis, Spiros DD, Branco, Miguel R, Harvey, Nicholas C, Cleal, Jane K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903835/
https://www.ncbi.nlm.nih.gov/pubmed/35256050
http://dx.doi.org/10.7554/eLife.71094