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Interferon α/β Decoy Receptor Encoded by a Variant in the Dryvax Smallpox Vaccine Contributes to Virulence and Correlates with Severe Vaccine Side Effects
Although providing long-lasting immunity, smallpox vaccination was associated with local and systemic reactions and rarely with severe complications, including progressive vaccinia and postvaccinia encephalitis. As the Dryvax smallpox vaccine consists of a population of variants, we investigated a p...
Autores principales: | Liu, Ruikang, Americo, Jeffrey L., Earl, Patricia L., Villani, Jack, Cotter, Catherine A., Moss, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903894/ https://www.ncbi.nlm.nih.gov/pubmed/35189701 http://dx.doi.org/10.1128/mbio.00102-22 |
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