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A pre-clinical model combining cryopreservation technique with precision-cut slice culture method to assess the in vitro drug response of hepatocellular carcinoma

Models considering hepatocellular carcinoma (HCC) complexity cannot be accurately replicated in routine cell lines or animal models. We aimed to evaluate the practicality of tissue slice culture by combining it with a cryopreservation technique. We prepared 0.3-mm-thick tissue slices by a microtome...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Wang, Zhen-Yu, Jing, Hong-Shu, Zhang, Hong-Dan, Yan, He-Xin, Fan, Jian-Xia, Zhai, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904079/
https://www.ncbi.nlm.nih.gov/pubmed/35179217
http://dx.doi.org/10.3892/ijmm.2022.5107