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A pre-clinical model combining cryopreservation technique with precision-cut slice culture method to assess the in vitro drug response of hepatocellular carcinoma
Models considering hepatocellular carcinoma (HCC) complexity cannot be accurately replicated in routine cell lines or animal models. We aimed to evaluate the practicality of tissue slice culture by combining it with a cryopreservation technique. We prepared 0.3-mm-thick tissue slices by a microtome...
Autores principales: | Zhang, Yuan, Wang, Zhen-Yu, Jing, Hong-Shu, Zhang, Hong-Dan, Yan, He-Xin, Fan, Jian-Xia, Zhai, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904079/ https://www.ncbi.nlm.nih.gov/pubmed/35179217 http://dx.doi.org/10.3892/ijmm.2022.5107 |
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