Structure-based virtual screening workflow to identify antivirals targeting HIV-1 capsid

We have identified novel HIV-1 capsid inhibitors targeting the PF74 binding site. Acting as the building block of the HIV-1 capsid core, the HIV-1 capsid protein plays an important role in the viral life cycle and is an attractive target for antiviral development. A structure-based virtual screening...

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Detalles Bibliográficos
Autores principales: Sun, Qinfang, Biswas, Avik, Vijayan, R. S. K., Craveur, Pierrick, Forli, Stefano, Olson, Arthur J., Castaner, Andres Emanuelli, Kirby, Karen A., Sarafianos, Stefan G., Deng, Nanjie, Levy, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904208/
https://www.ncbi.nlm.nih.gov/pubmed/35262811
http://dx.doi.org/10.1007/s10822-022-00446-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904208/
https://www.ncbi.nlm.nih.gov/pubmed/35262811
http://dx.doi.org/10.1007/s10822-022-00446-5

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