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Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway

Punicalagin, which is derived from pomegranate peel, is reported to exert growth-inhibitory effects against various cancers. However, the underlying mechanisms have not been elucidated. Human papillomavirus (HPV), a major oncovirus, utilizes the host autophagic machinery to support its replication....

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Detalles Bibliográficos
Autores principales: Xie, Xialin, Hu, Liuyi, Liu, Lulu, Wang, Jiuru, Liu, Yongai, Ma, Li, Sun, Guangying, Li, Changfei, Aisa, Haji Akber, Meng, Songdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904240/
https://www.ncbi.nlm.nih.gov/pubmed/35259676
http://dx.doi.org/10.1016/j.tranon.2022.101388