Cargando…

Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway

Punicalagin, which is derived from pomegranate peel, is reported to exert growth-inhibitory effects against various cancers. However, the underlying mechanisms have not been elucidated. Human papillomavirus (HPV), a major oncovirus, utilizes the host autophagic machinery to support its replication....

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Xialin, Hu, Liuyi, Liu, Lulu, Wang, Jiuru, Liu, Yongai, Ma, Li, Sun, Guangying, Li, Changfei, Aisa, Haji Akber, Meng, Songdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904240/ https://www.ncbi.nlm.nih.gov/pubmed/35259676 http://dx.doi.org/10.1016/j.tranon.2022.101388

Ejemplares similares

Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases
por: Xu, Yuxiu, et al.
Publicado: (2021)

Extracellular gp96 is a crucial mediator for driving immune hyperactivation and liver damage
por: Guan, Zeliang, et al.
Publicado: (2020)

Quercetin 3-O-(6″-O-E-caffeoyl)-β-D-glucopyranoside, a Flavonoid Compound, Promotes Melanogenesis through the Upregulation of MAPKs and Akt/GSK3β/β-Catenin Signaling Pathways
por: Liu, Changhai, et al.
Publicado: (2023)

Physiological and Immune Functions of Punicalagin
por: Venusova, Eva, et al.
Publicado: (2021)

Punicalagin Targets Atherosclerosis: Gene Expression Profiling of THP-1 Macrophages Treated with Punicalagin and Molecular Docking
por: Huwait, Etimad, et al.
Publicado: (2022)

Novel Furocoumarin Derivatives Stimulate Melanogenesis in B16 Melanoma Cells by Up-Regulation of MITF and TYR Family via Akt/GSK3β/β-Catenin Signaling Pathways
por: Niu, Chao, et al.
Publicado: (2018)

Anti-inflammatory effect of pomegranate flower in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages
por: Xu, Jianjun, et al.
Publicado: (2017)

Rapid Quantification and Quantitation of Alkaloids in Xinjiang Fritillaria by Ultra Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry
por: Mohammat, Aziz, et al.
Publicado: (2017)

Amine derivatives of furocoumarin induce melanogenesis by activating Akt/GSK-3β/β-catenin signal pathway
por: Zang, Deng, et al.
Publicado: (2019)

Preparation of novel 1,2,3-triazole furocoumarin derivatives via click chemistry and their anti-vitiligo activity
por: Niu, Chao, et al.
Publicado: (2019)

Study of Novel Furocoumarin Derivatives on Anti-Vitiligo Activity, Molecular Docking and Mechanism of Action
por: Niu, Chao, et al.
Publicado: (2022)

Nanostructured N, S, and P-Doped Elaeagnus Angustifolia Gum-Derived Porous Carbon with Electrodeposited Silver for Enhanced Electrochemical Sensing of Acetaminophen
por: Mamat, Xamxikamar, et al.
Publicado: (2023)

Newly Synthesized Punicalin and Punicalagin Nano-Prototypes Induce Breast Cancer Cytotoxicity Through ROS-Mediated Apoptosis
por: Abd-Rabou, Ahmed A, et al.
Publicado: (2022)

Crystal and molecular structure of jatrophane diterpenoid (2R,3R,4S,5R,7S,8S,9S,13S,14S,15R)-2,3,8,9-tetraacetoxy-5,14-bis(benzoyloxy)-15-hydroxy-7-(isobutanoyloxy)jatropha-6(17),11(E)-diene
por: Yang, Hequn, et al.
Publicado: (2019)

Chemical and Pharmacological Evaluation of Hulls of Prunus dulcis Nuts
por: Qureshi, Muhammad Nasimullah, et al.
Publicado: (2019)

Chemical constituents and their pharmacological activities of plants from Cichorium genus
por: Aisa, Haji Akber, et al.
Publicado: (2020)

Alisol B 23-acetate induces autophagic-dependent apoptosis in human colon cancer cells via ROS generation and JNK activation
por: Zhao, Yueliang, et al.
Publicado: (2017)

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction
por: Decuypere, Jean-Paul, et al.
Publicado: (2012)

Development of HPLC Protocol and Simultaneous Quantification of Four Free Flavonoids from Dracocephalum heterophyllum Benth.
por: Numonov, Sodik Rakhmonovich, et al.
Publicado: (2015)

Preparation of Magnetic Nanoliposomes of Sesquiterpene-Rich Fraction from Cichorium glandulosum and Its Tissue Distribution in Mice
por: Luo, Yuqin, et al.
Publicado: (2018)

Investigating the Antioxidant and Acetylcholinesterase Inhibition Activities of Gossypium herbaceam
por: Zhao, Yongxin, et al.
Publicado: (2013)

Chemical Composition, Antimicrobial and Antitumor Activities of the Essential Oils and Crude Extracts of Euphorbia macrorrhiza
por: Lin, Jianbo, et al.
Publicado: (2012)

Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer
por: Lu, Xueying, et al.
Publicado: (2017)

A Novel Furocoumarin Derivative, 5-((diethylamino)me-13 thyl)-3-phenyl-7H-furo [3,2-g] chromen-7-one Upregulates Melanin Synthesis via the Activation of cAMP/PKA and MAPKs Signal Pathway: In Vitro and In Vivo Study
por: Zang, Deng, et al.
Publicado: (2022)

Comprehensive Study of Components and Antimicrobial Properties of Essential Oil Extracted from Carum carvi L. Seeds
por: Liu, Changhai, et al.
Publicado: (2023)

Anti-proliferation of triple-negative breast cancer cells with physagulide P: ROS/JNK signaling pathway induces apoptosis and autophagic cell death
por: Yu, Pei, et al.
Publicado: (2017)

eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus
por: Li, Yanrong, et al.
Publicado: (2019)

Potential anti-vitiligo properties of cynarine extracted from Vernonia anthelmintica (L.) Willd
por: Mamat, Nuramina, et al.
Publicado: (2018)

Kursi Wufarikun Ziyabit Improves the Physiological Changes by Regulating Endoplasmic Reticulum Stress in the Type 2 Diabetes db/db Mice
por: Edirs, Salamet, et al.
Publicado: (2021)

Punicalagin in Cancer Prevention—Via Signaling Pathways Targeting
por: Berdowska, Izabela, et al.
Publicado: (2021)

Antibiofilm effects of punicalagin against Staphylococcus aureus in vitro
por: Xu, Yunfeng, et al.
Publicado: (2023)

N-Acetylcysteine Attenuates Ischemia-Reperfusion-Induced Apoptosis and Autophagy in Mouse Liver via Regulation of the ROS/JNK/Bcl-2 Pathway
por: Wang, Chengfen, et al.
Publicado: (2014)

(5R,8R)-2-(3,8-Dimethyl-2-oxo-1,2,4,5,6,7,8,8a-octahydroazulen-5-yl)acrylic acid (rupestonic acid)
por: Aisa, Haji Akber, et al.
Publicado: (2008)

2,3-Trimethylene-7,8-dihydropyrrolo[1,2-a]thieno[2,3-d]pyrimidin-4(6H)-one
por: Bozorov, Khurshed, et al.
Publicado: (2013)

Effect of Chlorogenic Acid on Melanogenesis of B16 Melanoma Cells
por: Li, Hao-Rong, et al.
Publicado: (2014)

Optimization of Extraction Process for Antidiabetic and Antioxidant Activities of Kursi Wufarikun Ziyabit Using Response Surface Methodology and Quantitative Analysis of Main Components
por: Edirs, Salamet, et al.
Publicado: (2017)

Study on Lavender Essential Oil Chemical Compositions by GC-MS and Improved pGC
por: Dong, Guangyao, et al.
Publicado: (2020)

Pharmacokinetic Study and Metabolite Identification of CAM106 in Rats by Validated UHPLC-MS/MS
por: Xi, Ruqi, et al.
Publicado: (2023)

Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages
por: Tsukuba, Takayuki, et al.
Publicado: (2013)

Punicalagin Induces Serum Low-Density Lipoprotein Influx to Macrophages
por: Atrahimovich, Dana, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_smttqrim1aqvugmib1mlhcv6qs