EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma

Gene expression is regulated by promoters and enhancers marked by histone H3 lysine 27 acetylation (H3K27ac), which is established by the paralogous histone acetyltransferases (HAT) EP300 and CBP. These enzymes display overlapping regulatory roles in untransformed cells, but less characterized roles...

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Detalles Bibliográficos
Autores principales: Durbin, Adam D., Wang, Tingjian, Wimalasena, Virangika K., Zimmerman, Mark W., Li, Deyao, Dharia, Neekesh V., Mariani, Luca, Shendy, Noha A.M., Nance, Stephanie, Patel, Anand G., Shao, Ying, Mundada, Maya, Maxham, Lily, Park, Paul M.C., Sigua, Logan H., Morita, Ken, Conway, Amy Saur, Robichaud, Amanda L., Perez-Atayde, Antonio R., Bikowitz, Melissa J., Quinn, Taylor R., Wiest, Olaf, Easton, John, Schönbrunn, Ernst, Bulyk, Martha L., Abraham, Brian J., Stegmaier, Kimberly, Look, A. Thomas, Qi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904277/
https://www.ncbi.nlm.nih.gov/pubmed/34772733
http://dx.doi.org/10.1158/2159-8290.CD-21-0385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904277/
https://www.ncbi.nlm.nih.gov/pubmed/34772733
http://dx.doi.org/10.1158/2159-8290.CD-21-0385

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