Tcf1 preprograms the mobilization of glycolysis in central memory CD8(+) T cells during recall responses

The mechanisms underlying the heightened protection mediated by central memory CD8(+) T (T(cm)) cells remain unclear. Here we show that the transcription factor Tcf1 was required in resting T(cm) cells to generate secondary effector CD8(+) T cells and to clear pathogen during recall responses. Recal...

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Detalles Bibliográficos
Autores principales: Shan, Qiang, Hu, Shengen Shawn, Zhu, Shaoqi, Chen, Xia, Badovinac, Vladimir P., Peng, Weiqun, Zang, Chongzhi, Xue, Hai-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904300/
https://www.ncbi.nlm.nih.gov/pubmed/35190717
http://dx.doi.org/10.1038/s41590-022-01131-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904300/
https://www.ncbi.nlm.nih.gov/pubmed/35190717
http://dx.doi.org/10.1038/s41590-022-01131-3

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