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Tcf1 preprograms the mobilization of glycolysis in central memory CD8(+) T cells during recall responses
The mechanisms underlying the heightened protection mediated by central memory CD8(+) T (T(cm)) cells remain unclear. Here we show that the transcription factor Tcf1 was required in resting T(cm) cells to generate secondary effector CD8(+) T cells and to clear pathogen during recall responses. Recal...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904300/ https://www.ncbi.nlm.nih.gov/pubmed/35190717 http://dx.doi.org/10.1038/s41590-022-01131-3 |