MQuad enables clonal substructure discovery using single cell mitochondrial variants

Mitochondrial mutations are increasingly recognised as informative endogenous genetic markers that can be used to reconstruct cellular clonal structure using single-cell RNA or DNA sequencing data. However, identifying informative mtDNA variants in noisy and sparse single-cell sequencing data is sti...

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Detalles Bibliográficos
Autores principales: Kwok, Aaron Wing Cheung, Qiao, Chen, Huang, Rongting, Sham, Mai-Har, Ho, Joshua W. K., Huang, Yuanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904442/
https://www.ncbi.nlm.nih.gov/pubmed/35260582
http://dx.doi.org/10.1038/s41467-022-28845-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904442/
https://www.ncbi.nlm.nih.gov/pubmed/35260582
http://dx.doi.org/10.1038/s41467-022-28845-0

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