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Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis

Gastric cancer (GC) is a heterogeneous disease with poor prognosis. Tumor-derived extracellular vesicles (EVs) assume a role in intercellular communication by carrying various molecules, including proteins, RNA, and DNAs, which has been identified to exhibit oncogenic effect in GC. Therefore, this r...

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Detalles Bibliográficos
Autores principales: Li, Bopei, Chen, Yeyang, Liang, Liang, Wang, Ye, Huang, Weijia, Zhao, Kun, Liu, Siyu, Deng, Guofei, Chen, Junqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904444/
https://www.ncbi.nlm.nih.gov/pubmed/35260554
http://dx.doi.org/10.1038/s41419-021-04446-5