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An intra-cytoplasmic route for SARS-CoV-2 transmission unveiled by Helium-ion microscopy

SARS-CoV-2 virions enter the host cells by docking their spike glycoproteins to the membrane-bound Angiotensin Converting Enzyme 2. After intracellular assembly, the newly formed virions are released from the infected cells to propagate the infection, using the extra-cytoplasmic ACE2 docking mechani...

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Detalles Bibliográficos
Autores principales: Merolli, Antonio, Kasaei, Leila, Ramasamy, Santhamani, Kolloli, Afsal, Kumar, Ranjeet, Subbian, Selvakumar, Feldman, Leonard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904465/
https://www.ncbi.nlm.nih.gov/pubmed/35260703
http://dx.doi.org/10.1038/s41598-022-07867-0