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A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

Pre-erythrocytic malaria vaccines that induce high-titer, durable antibody responses can potentially provide protection from infection. Here, we engineered a virus-like particle (VLP)-based vaccine targeting a recently described vulnerable epitope at the N-terminus of the central repeat region of th...

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Detalles Bibliográficos
Autores principales:	Jelínková, Lucie, Flores-Garcia, Yevel, Shapiro, Sarah, Roberts, Bryce T., Petrovsky, Nikolai, Zavala, Fidel, Chackerian, Bryce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904524/ https://www.ncbi.nlm.nih.gov/pubmed/35260593 http://dx.doi.org/10.1038/s41541-022-00457-1

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