Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors

Despite limited reports on glutamine methylation, methylated glutamine is found to be highly conserved in a "GGQ" motif in both prokaryotes and eukaryotes. In bacteria, glutamine methylation of peptide chain release factors 1/2 (RF1/2) by the enzyme PrmC is essential for translational term...

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Detalles Bibliográficos
Autores principales: Fang, Qi, Kimura, Yusuke, Shimazu, Tadahiro, Suzuki, Takehiro, Yamada, Ayumi, Dohmae, Naoshi, Iwasaki, Shintaro, Shinkai, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904536/
https://www.ncbi.nlm.nih.gov/pubmed/35260756
http://dx.doi.org/10.1038/s41598-022-08061-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904536/
https://www.ncbi.nlm.nih.gov/pubmed/35260756
http://dx.doi.org/10.1038/s41598-022-08061-y

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