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Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors
Despite limited reports on glutamine methylation, methylated glutamine is found to be highly conserved in a "GGQ" motif in both prokaryotes and eukaryotes. In bacteria, glutamine methylation of peptide chain release factors 1/2 (RF1/2) by the enzyme PrmC is essential for translational term...
Autores principales: | Fang, Qi, Kimura, Yusuke, Shimazu, Tadahiro, Suzuki, Takehiro, Yamada, Ayumi, Dohmae, Naoshi, Iwasaki, Shintaro, Shinkai, Yoichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904536/ https://www.ncbi.nlm.nih.gov/pubmed/35260756 http://dx.doi.org/10.1038/s41598-022-08061-y |
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