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A tool for translating polygenic scores onto the absolute scale using summary statistics

There is growing interest in the clinical application of polygenic scores as their predictive utility increases for a range of health-related phenotypes. However, providing polygenic score predictions on the absolute scale is an important step for their safe interpretation. We have developed a metho...

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Detalles Bibliográficos
Autores principales: Pain, Oliver, Gillett, Alexandra C., Austin, Jehannine C., Folkersen, Lasse, Lewis, Cathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904577/
https://www.ncbi.nlm.nih.gov/pubmed/34983942
http://dx.doi.org/10.1038/s41431-021-01028-z