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Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction

The northern white rhinoceros (NWR) is probably the earth’s most endangered mammal. To rescue the functionally extinct species, we aim to employ induced pluripotent stem cells (iPSCs) to generate gametes and subsequently embryos in vitro. To elucidate the regulation of pluripotency and differentiati...

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Detalles Bibliográficos
Autores principales: Zywitza, Vera, Rusha, Ejona, Shaposhnikov, Dmitry, Ruiz-Orera, Jorge, Telugu, Narasimha, Rishko, Valentyna, Hayashi, Masafumi, Michel, Geert, Wittler, Lars, Stejskal, Jan, Holtze, Susanne, Göritz, Frank, Hermes, Robert, Wang, Jichang, Izsvák, Zsuzsanna, Colleoni, Silvia, Lazzari, Giovanna, Galli, Cesare, Hildebrandt, Thomas B., Hayashi, Katsuhiko, Diecke, Sebastian, Drukker, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904600/
https://www.ncbi.nlm.nih.gov/pubmed/35260583
http://dx.doi.org/10.1038/s41598-022-07059-w