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Engineering an acetoacetyl-CoA reductase from Cupriavidus necator toward NADH preference under physiological conditions
The coupling of PHB generation with NADH reoxidation is required to generate PHB as a fermentation product. A fundamental trait to accomplish this feature is to express a functional NADH-preferring acetoacetyl-CoA reductase, engaged in PHB accumulation. One way to obtain such a reductase is by engin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904767/ https://www.ncbi.nlm.nih.gov/pubmed/35260659 http://dx.doi.org/10.1038/s41598-022-07663-w |