CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses

Cap-adjacent nucleotides of animal, protist and viral mRNAs can be O-methylated at the 2‘ position of the ribose (cOMe). The functions of cOMe in animals, however, remain largely unknown. Here we show that the two cap methyltransferases (CMTr1 and CMTr2) of Drosophila can methylate the ribose of the...

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Detalles Bibliográficos
Autores principales: Haussmann, Irmgard U., Wu, Yanying, Nallasivan, Mohanakarthik P., Archer, Nathan, Bodi, Zsuzsanna, Hebenstreit, Daniel, Waddell, Scott, Fray, Rupert, Soller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904806/
https://www.ncbi.nlm.nih.gov/pubmed/35260552
http://dx.doi.org/10.1038/s41467-022-28549-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904806/
https://www.ncbi.nlm.nih.gov/pubmed/35260552
http://dx.doi.org/10.1038/s41467-022-28549-5

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