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Histone H2AX promotes metastatic progression by preserving glycolysis via hexokinase-2

Genomic stability is essential for organismal development, cellular homeostasis, and survival. The DNA double-strand breaks are particularly deleterious, creating an environment prone to cellular transformation and oncogenic activation. The histone variant H2AX is an essential component of the nucle...

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Detalles Bibliográficos
Autores principales: Liu, Yue, Li, Haojian, Wilson, Crystal N., Bai, Hui Jen, Boufraqech, Myriem, Weyemi, Urbain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904825/
https://www.ncbi.nlm.nih.gov/pubmed/35260660
http://dx.doi.org/10.1038/s41598-022-07675-6