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Histone H2AX promotes metastatic progression by preserving glycolysis via hexokinase-2
Genomic stability is essential for organismal development, cellular homeostasis, and survival. The DNA double-strand breaks are particularly deleterious, creating an environment prone to cellular transformation and oncogenic activation. The histone variant H2AX is an essential component of the nucle...
Autores principales: | Liu, Yue, Li, Haojian, Wilson, Crystal N., Bai, Hui Jen, Boufraqech, Myriem, Weyemi, Urbain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904825/ https://www.ncbi.nlm.nih.gov/pubmed/35260660 http://dx.doi.org/10.1038/s41598-022-07675-6 |
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