Oral cancer induced TRPV1 sensitization is mediated by PAR(2) signaling in primary afferent neurons innervating the cancer microenvironment

Oral cancer patients report sensitivity to spicy foods and liquids. The mechanism responsible for chemosensitivity induced by oral cancer is not known. We simulate oral cancer-induced chemosensitivity in a xenograft oral cancer mouse model using two-bottle choice drinking and conditioned place avers...

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Detalles Bibliográficos
Autores principales: Scheff, Nicole N., Wall, Ian M., Nicholson, Sam, Williams, Hannah, Chen, Elyssa, Tu, Nguyen H., Dolan, John C., Liu, Cheng Z., Janal, Malvin N., Bunnett, Nigel W., Schmidt, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904826/
https://www.ncbi.nlm.nih.gov/pubmed/35260737
http://dx.doi.org/10.1038/s41598-022-08005-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904826/
https://www.ncbi.nlm.nih.gov/pubmed/35260737
http://dx.doi.org/10.1038/s41598-022-08005-6

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