Impact of deleterious missense PRKCI variants on structural and functional dynamics of protein

Protein kinase C iota (PKC(ɩ)) is a novel protein containing 596 amino acids and is also a member of atypical kinase family. The role of PKC(ɩ) has been explored in neurodegenerative diseases, neuroblastoma, ovarian and pancreatic cancers. Single nucleotide polymorphisms (SNPs) have not been studied...

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Hania, Khan, Khushbukhat, Khan, Naila, Badshah, Yasmin, Ashraf, Naeem Mahmood, Shabbir, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904829/
https://www.ncbi.nlm.nih.gov/pubmed/35260606
http://dx.doi.org/10.1038/s41598-022-07526-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904829/
https://www.ncbi.nlm.nih.gov/pubmed/35260606
http://dx.doi.org/10.1038/s41598-022-07526-4

Ejemplares similares