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Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma

Aberrant methylation of genomic DNA has been reported in many cancers. Specific DNA methylation patterns have been shown to provide clinically useful prognostic information and define molecular disease subtypes with different response to therapy and long-term outcome. Osteosarcoma is an aggressive m...

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Detalles Bibliográficos
Autores principales: Lietz, Christopher E., Newman, Erik T., Kelly, Andrew D., Xiang, David H., Zhang, Ziying, Luscko, Caroline A., Lozano-Calderon, Santiago A., Ebb, David H., Raskin, Kevin A., Cote, Gregory M., Choy, Edwin, Nielsen, G. Petur, Haibe-Kains, Benjamin, Aryee, Martin J., Spentzos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904843/
https://www.ncbi.nlm.nih.gov/pubmed/35260776
http://dx.doi.org/10.1038/s42003-022-03117-1