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The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer
SLC7A11/xCT is an antiporter that mediates the uptake of extracellular cystine in exchange for glutamate. Cystine is reduced to cysteine, which is a rate-limiting precursor in glutathione synthesis; a process that protects cells from oxidative stress and is, therefore, critical to cell growth, proli...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904967/ https://www.ncbi.nlm.nih.gov/pubmed/35280777 http://dx.doi.org/10.3389/fonc.2022.858462 |