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Down regulated oncogene KIF2C inhibits growth, invasion, and metastasis of hepatocellular carcinoma through the Ras/MAPK signaling pathway and epithelial-to-mesenchymal transition

BACKGROUND: Hepatocellular carcinoma (HCC) is the leading cause of cancer death. Kinesin family member 2C (KIF2C) has been shown as oncogene in a variety of tumors. However, its role in HCC remains unclear. METHODS: In this study, the expression level of KIF2C in HCC was detected by immunohistochemi...

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Detalles Bibliográficos
Autores principales: Mo, Shutian, Fang, Dalang, Zhao, Shuqi, Thai Hoa, Pham Thi, Zhou, Caifu, Liang, Tianyi, He, Yongfei, Yu, Tingdong, Chen, Yuanyuan, Qin, Wei, Han, Quanfa, Su, Hao, Zhu, Guangzhi, Luo, Xiaoling, Peng, Tao, Han, Chuangye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904974/
https://www.ncbi.nlm.nih.gov/pubmed/35284538
http://dx.doi.org/10.21037/atm-21-6240