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Inhibition of protein kinase C alpha attenuates lipopolysaccharide-triggered acute lung injury by alleviating the hyperinflammatory response and oxidative stress

BACKGROUND: The currently available treatment methods are ineffective in reducing mortality or improving outcomes in acute lung injury (ALI). The activation of protein kinase C alpha (PKCα) has recently been implicated in ALI development. We explored the potential therapeutic outcomes of PKCα inhibi...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Lin, Pengcheng, Nan, Wengang, Su, Shanshan, Zheng, Hong, Gao, Hongchang, Zhang, Dan, Li, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904993/
https://www.ncbi.nlm.nih.gov/pubmed/35284551
http://dx.doi.org/10.21037/atm-21-6497