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Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers
Telomeres are nucleoprotein structures that cap the ends of linear chromosomes. Telomeric DNA comprises terminal tracts of G-rich tandem repeats, which are inherently difficult for the replication machinery to navigate. Structural aberrations that promote activation of the alternative lengthening of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905155/ https://www.ncbi.nlm.nih.gov/pubmed/35259951 http://dx.doi.org/10.1098/rsob.220011 |