Cargando…

Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers

Telomeres are nucleoprotein structures that cap the ends of linear chromosomes. Telomeric DNA comprises terminal tracts of G-rich tandem repeats, which are inherently difficult for the replication machinery to navigate. Structural aberrations that promote activation of the alternative lengthening of...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Robert, Pickett, Hilda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905155/
https://www.ncbi.nlm.nih.gov/pubmed/35259951
http://dx.doi.org/10.1098/rsob.220011