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Reconstitution of an active human CENP-E motor

CENP-E is a large kinesin motor protein which plays pivotal roles in mitosis by facilitating chromosome capture and alignment, and promoting microtubule flux in the spindle. So far, it has not been possible to obtain active human CENP-E to study its molecular properties. Xenopus CENP-E motor has bee...

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Detalles Bibliográficos
Autores principales: Craske, Benjamin, Legal, Thibault, Welburn, Julie P. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905165/
https://www.ncbi.nlm.nih.gov/pubmed/35259950
http://dx.doi.org/10.1098/rsob.210389