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Canagliflozin Prevents Lipid Accumulation, Mitochondrial Dysfunction, and Gut Microbiota Dysbiosis in Mice With Diabetic Cardiovascular Disease

Type 2 diabetes mellitus (T2DM) is associated with cardiovascular disease (CVD) and sodium glucose cotransporter 2 inhibitors, as oral medications for T2DM treatment have shown the potential to improve vascular dysfunction. The aim of this study was to evaluate the ability of canagliflozin (Cana) to...

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Detalles Bibliográficos
Autores principales: Wang, Xueliang, Wang, Zhe, Liu, Di, Jiang, Hao, Cai, Chao, Li, Guoyun, Yu, Guangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905428/
https://www.ncbi.nlm.nih.gov/pubmed/35281938
http://dx.doi.org/10.3389/fphar.2022.839640