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Verapamil Alleviates Myocardial Ischemia/Reperfusion Injury by Attenuating Oxidative Stress via Activation of SIRT1

Myocardial ischemia/reperfusion (I/R) injury is a potential complication of ischemic heart disease after recanalization. One of the primary reasons for I/R injury is the excessive accumulation of reactive oxygen species (ROS) in cardiomyocytes. Verapamil, a classic calcium channel blocker, has the p...

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Detalles Bibliográficos
Autores principales: Bao, Mi, Huang, Weiyi, Zhao, Yang, Fang, Xinzhe, Zhang, Yanmei, Gao, Fenfei, Huang, Danmei, Wang, Bin, Shi, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905444/
https://www.ncbi.nlm.nih.gov/pubmed/35281891
http://dx.doi.org/10.3389/fphar.2022.822640