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Impact of a Single Nucleotide Polymorphism on the 3D Protein Structure and Ubiquitination Activity of E3 Ubiquitin Ligase Arkadia

Single nucleotide polymorphisms (SNPs) are genetic variations which can play a vital role in the study of human health. SNP studies are often used to identify point mutations that are associated with diseases. Arkadia (RNF111) is an E3 ubiquitin ligase that enhances transforming growth factor-beta (...

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Detalles Bibliográficos
Autores principales: Birkou, Maria, Raptis, Vasilios, Marousis, Konstantinos D., Tsevis, Athanasios, Bourikas, Kyriakos, Bentrop, Detlef, Episkopou, Vasso, Spyroulias, Georgios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905620/
https://www.ncbi.nlm.nih.gov/pubmed/35281275
http://dx.doi.org/10.3389/fmolb.2022.844129