Tumor-Derived Extracellular Vesicles Activate Normal Human Fibroblasts to a Cancer-Associated Fibroblast-Like Phenotype, Sustaining a Pro-Tumorigenic Microenvironment

Fibroblasts in the tumor microenvironment have been proven to actively participate in tumor progression; they can be “educated” by cancer cells acquiring an activated state and, as such, are identified as cancer-associated fibroblasts (CAFs); CAFs, in turn, remodel tumor stroma to be more advantageo...

Descripción completa

Detalles Bibliográficos
Autores principales: Giusti, Ilaria, Di Francesco, Marianna, Poppa, Giuseppina, Esposito, Letizia, D’Ascenzo, Sandra, Dolo, Vincenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905682/
https://www.ncbi.nlm.nih.gov/pubmed/35280782
http://dx.doi.org/10.3389/fonc.2022.839880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905682/
https://www.ncbi.nlm.nih.gov/pubmed/35280782
http://dx.doi.org/10.3389/fonc.2022.839880

Ejemplares similares