Cargando…

GATA2 deficiency elevates interferon regulatory factor-8 to subvert a progenitor cell differentiation program

Cell type-specific transcription factors control stem and progenitor cell transitions by establishing networks containing hundreds of genes and proteins. Network complexity renders it challenging to discover essential versus modulatory or redundant components. This scenario is exemplified by GATA2 r...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Kirby D., Soukup, Alexandra A., Bresnick, Emery H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905696/
https://www.ncbi.nlm.nih.gov/pubmed/35008108
http://dx.doi.org/10.1182/bloodadvances.2021006182