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GATA2 deficiency elevates interferon regulatory factor-8 to subvert a progenitor cell differentiation program
Cell type-specific transcription factors control stem and progenitor cell transitions by establishing networks containing hundreds of genes and proteins. Network complexity renders it challenging to discover essential versus modulatory or redundant components. This scenario is exemplified by GATA2 r...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905696/ https://www.ncbi.nlm.nih.gov/pubmed/35008108 http://dx.doi.org/10.1182/bloodadvances.2021006182 |