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Dual-Targeted Self-Assembled DNA Hydrogels Decorated With Multivalent Aptamers Loaded With DOX for Anticancer Therapy

Chemotherapy, as one of the principal modalities for cancer therapy, is limited by its non-specific and inefficient delivery to tumors. To overcome these limitations, we report herein a dual-targeted aptamer-decorated DNA hydrogel system (DTA-H) to achieve efficient, stable, and targeted delivery of...

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Detalles Bibliográficos
Autores principales: Jin, Fangfang, Zeng, Qian, Qian, Husun, Zhang, Dian, Wei, Yu, Wang, Yange, Chai, Chengsen, Cheng, Wei, Ding, Shijia, Chen, Tingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905714/
https://www.ncbi.nlm.nih.gov/pubmed/35281887
http://dx.doi.org/10.3389/fphar.2022.807498