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DNMT1 is a negative regulator of osteogenesis

The role and underlying mechanisms of DNA methylation in osteogenesis/chondrogenesis remain poorly understood. We here reveal DNA methyltransferase 1 (DNMT1), which is responsible for copying DNA methylation onto the newly synthesized DNA strand after DNA replication, is overexpressed in sponge bone...

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Detalles Bibliográficos
Autores principales: Tao, Chen, Liu, Jia, Li, Ziqi, Lai, Pinglin, Zhang, Sheng, Qu, Jiankun, Tang, Yujin, Liu, Anling, Zou, Zhipeng, Bai, Xiaochun, Li, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905718/
https://www.ncbi.nlm.nih.gov/pubmed/35238333
http://dx.doi.org/10.1242/bio.058534