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RAS pathway regulation in melanoma

Activating mutations in RAS genes are the most common genetic driver of human cancers. Yet, drugging this small GTPase has proven extremely challenging and therapeutic strategies targeting these recurrent alterations have long had limited success. To circumvent this difficulty, research has focused...

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Detalles Bibliográficos
Autores principales: Al Mahi, Amira, Ablain, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905719/
https://www.ncbi.nlm.nih.gov/pubmed/35234863
http://dx.doi.org/10.1242/dmm.049229