Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes

BACKGROUND: Blood plasma proteins play an important role in immune defense against pathogens, including cytokine signaling, the complement system, and the acute-phase response. Recent large-scale studies have reported genetic (i.e., protein quantitative trait loci, pQTLs) and non-genetic factors, su...

Descripción completa

Detalles Bibliográficos
Autores principales: Caron, Barthelemy, Patin, Etienne, Rotival, Maxime, Charbit, Bruno, Albert, Matthew L., Quintana-Murci, Lluis, Duffy, Darragh, Rausell, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905727/
https://www.ncbi.nlm.nih.gov/pubmed/35264221
http://dx.doi.org/10.1186/s13073-022-01032-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905727/
https://www.ncbi.nlm.nih.gov/pubmed/35264221
http://dx.doi.org/10.1186/s13073-022-01032-y

Ejemplares similares