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BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos

BACKGROUND: During mammalian preimplantation development, as the fertilized egg develops and differentiates, three cell lineages become specified: trophectoderm (TE), epiblast, and primitive endoderm (PrE). Through two steps of cell fate decisions, 16-cell blastomeres develop into TE and an inner ce...

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Detalles Bibliográficos
Autores principales: Tsume-Kajioka, Mami, Kimura-Yoshida, Chiharu, Mochida, Kyoko, Ueda, Yoko, Matsuo, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905768/
https://www.ncbi.nlm.nih.gov/pubmed/35264162
http://dx.doi.org/10.1186/s12915-022-01251-0