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BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos
BACKGROUND: During mammalian preimplantation development, as the fertilized egg develops and differentiates, three cell lineages become specified: trophectoderm (TE), epiblast, and primitive endoderm (PrE). Through two steps of cell fate decisions, 16-cell blastomeres develop into TE and an inner ce...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905768/ https://www.ncbi.nlm.nih.gov/pubmed/35264162 http://dx.doi.org/10.1186/s12915-022-01251-0 |