The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation

BACKGROUND: Aseptic Loosening (AL) following periprosthetic osteolysis is the main long-term complication after total joint arthroplasty (TJA). However, there is rare effective treatment except for revision surgery, which is costly and painful to the patients. In recent years, the ketone body β-hydr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yanglin, Teng, Yun, Zhang, Chenhui, Pan, Ying, Zhang, Qin, Zhu, Xu, Liu, Naicheng, Su, Xinlin, Lin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905851/
https://www.ncbi.nlm.nih.gov/pubmed/35264201
http://dx.doi.org/10.1186/s12951-022-01320-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905851/
https://www.ncbi.nlm.nih.gov/pubmed/35264201
http://dx.doi.org/10.1186/s12951-022-01320-0

Ejemplares similares