Visualization of the process of a nanocarrier-mediated gene delivery: stabilization, endocytosis and endosomal escape of genes for intracellular spreading

Nanoparticles have been widely applied as gene carrier for improving RNA interference (RNAi) efficiency in medical and agricultural fields. However, the mechanism and delivery process of nanoparticle-mediated RNAi is not directly visualized and elucidated. Here we synthesized a star polymer (SPc) co...

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Detalles Bibliográficos
Autores principales: Ma, Zhongzheng, Zheng, Yang, Chao, Zijian, Chen, Hongtao, Zhang, Yunhui, Yin, Meizhen, Shen, Jie, Yan, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905852/
https://www.ncbi.nlm.nih.gov/pubmed/35264206
http://dx.doi.org/10.1186/s12951-022-01336-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905852/
https://www.ncbi.nlm.nih.gov/pubmed/35264206
http://dx.doi.org/10.1186/s12951-022-01336-6

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