Cargando…

Generalizable design parameters for soluble T cell receptor-based T cell engagers

While most biological and cellular immunotherapies recognize extracellular targets, T cell receptor (TCR) therapeutics are unique in their ability to recognize the much larger pool of intracellular antigens found on virus-infected or cancerous cells. Recombinant T cell receptor (rTCR)-based therapeu...

Descripción completa

Detalles Bibliográficos
Autores principales: Froning, Karen J, Sereno, Arlene, Huang, Flora, Demarest, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905924/
https://www.ncbi.nlm.nih.gov/pubmed/35260435
http://dx.doi.org/10.1136/jitc-2021-004281