Treatment with ddAVP improves platelet-based coagulation in a rat model of traumatic hemorrhagic shock

OBJECTIVES: Trauma-induced hemorrhagic shock is characterized by increased endothelial permeability and coagulopathy. Vasopressin analog ddAVP (desmopressin) acts by reorganizing and redistributing adhesive and tight junction molecules, enhancing endothelial barrier function. Furthermore, ddAVP incr...

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Detalles Bibliográficos
Autores principales: Wirtz, Mathijs R, Roelofs, Joris J, Goslings, J Carel, Juffermans, Nicole P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905935/
https://www.ncbi.nlm.nih.gov/pubmed/35340703
http://dx.doi.org/10.1136/tsaco-2021-000852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905935/
https://www.ncbi.nlm.nih.gov/pubmed/35340703
http://dx.doi.org/10.1136/tsaco-2021-000852

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