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Treatment with ddAVP improves platelet-based coagulation in a rat model of traumatic hemorrhagic shock
OBJECTIVES: Trauma-induced hemorrhagic shock is characterized by increased endothelial permeability and coagulopathy. Vasopressin analog ddAVP (desmopressin) acts by reorganizing and redistributing adhesive and tight junction molecules, enhancing endothelial barrier function. Furthermore, ddAVP incr...
Autores principales: | Wirtz, Mathijs R, Roelofs, Joris J, Goslings, J Carel, Juffermans, Nicole P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905935/ https://www.ncbi.nlm.nih.gov/pubmed/35340703 http://dx.doi.org/10.1136/tsaco-2021-000852 |
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