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PBMC CDC42 reveals the disease activity and treatment efficacy of TNF inhibitor in patients with ankylosing spondylitis

OBJECTIVE: Cell division cycle 42 (CDC42) regulates the polarization of M2 macrophage and maintains the T cell homeostasis, to participate in multiple autoimmune diseases, while its clinical involvement in ankylosing spondylitis (AS) remains unclear. Hence, the current study aimed to investigate the...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Jin, Du, Mou, Xiaoyue, Ye, Hengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906019/
https://www.ncbi.nlm.nih.gov/pubmed/35104386
http://dx.doi.org/10.1002/jcla.24267